This formula was developed by Doctor Albert Kligman, hence its name. He associated three components that help fight against the visibility of dark spots. Hydroquinone, hydrocortisone and retinoic acid act in synergy. The depigmentation power of these active ingredients makes it possible to act on the different stages of skin pigmentation. Kligman’s Trio is considered to be a drug, however the composition of the trio is a major source of inspiration for dermo-cosmetic laboratories for the development of cosmetic serums and creams.

Hydroquinone is an organic compound that is also found under the name of benzene-1, 4-diol. This aqueous solution is used by application to the skin to lighten the latter, its application reduces the brown pigment load. Hydroquinone comes in the form of white or colorless crystals. This active ingredient is found in the composition of products which aim to lighten dark spots on the skin. Products that contain high concentrations of hydroquinone should be used with caution and only on the advice of a dermatologist or healthcare professional. There are some risks in using a product with a hydroquinone concentration greater than 2%. This active works by reducing the production of melanin, which brightens the skin.

Hydrocortisone offers an anti-inflammatory action and allows the skin to better withstand the treatments administered. Hydrocortisone is often prescribed to treat allergic reactions or skin problems, it helps reduce inflammation and irritation.

Retinoic acid accelerates cell renewal in the skin, so hyper-pigmented cells are eliminated more quickly.